FemiCore Ingredients: A Reference Sheet for All Nine, With the Evidence and the Gaps

This page is a lookup sheet for the FemiCore formula. Every ingredient gets the same three checks: what it is, what the research we reviewed shows, and what the label does not tell you. If you would rather read the story of the formula from start to finish, our longer article on the FemiCore ingredients list covers it in prose.

Three rules for reading this sheet

Keep these in mind for every entry below.

• Ingredient research is not product research. The label says “Clinically researched ingredients”. That refers to the ingredients in general. No trial of the finished FemiCore formula exists.
• No amounts are given. All nine sit in a proprietary blend, so we cannot check any of them against the amounts used in studies.
• Most of the human data is about infections. Cranberry, bearberry and the best Lactobacillus crispatus trial looked at urinary tract infections. FemiCore is marketed mainly for bladder control, and none of that research measured leaks or urgency.

Quick facts on the capsule:

• Format: 30 capsules per bottle, one bottle lasts one month
• How the seller says to take it: 1 capsule every morning with a big glass of water
• Blend: proprietary, ingredient names only
• Seller statements: no stimulants, non-GMO
• Label claims: “Healthy urinary system”, “Bladder control support”, “Microbiome balance”

Summary table

#	Ingredient	Group	Best human evidence we found	Relevance to bladder control	Amount on label
1	Mimosa pudica	Plant	None (lab and animal only)	Not studied in people	Not shown
2	Bearberry (uva ursi)	Plant leaf	Limited and mixed, for urinary infection	Not studied for leaks	Not shown
3	Cranberry extract	Fruit extract	2023 Cochrane review on repeat UTIs	Studied for infections, not leaks	Not shown, no PAC figure
4	Granular berberine	Plant compound	Good data for blood sugar and cholesterol	Bladder evidence lacking	Not shown
5	Lactobacillus crispatus	Probiotic	Small trial of a vaginal product for repeat UTIs	Indirect	No CFU, no strain code
6	Lactobacillus acidophilus	Probiotic	Not tested for bladder symptoms in what we reviewed	Unknown	No CFU, no strain code
7	Lactobacillus plantarum	Probiotic	Not tested for bladder symptoms in what we reviewed	Unknown	No CFU, no strain code
8	Lactobacillus gasseri	Probiotic	Not tested for bladder symptoms in what we reviewed	Unknown	No CFU, no strain code
9	Lactobacillus casei	Probiotic	Not tested for bladder symptoms in what we reviewed	Unknown	No CFU, no strain code

The four plant ingredients

Mimosa pudica

What it is. A plant ingredient, listed first in the blend.

What research shows. Lab and animal studies report anti-inflammatory, antimicrobial and antispasmodic effects. We found no human trials for bladder symptoms. Of the nine ingredients, this one has the thinnest evidence.

Not disclosed. The amount per capsule.

Bearberry (uva ursi)

What it is. A leaf herb that contains arbutin. In the body, arbutin is turned into hydroquinone, which ends up in the urine and is antibacterial in lab tests.

What research shows. Human evidence is limited and mixed. European herbal regulators accept it as a traditional remedy for mild lower urinary complaints, but only in short courses of about a week, not for continuous use.

The mismatch. FemiCore is a daily capsule, and the vendor advises taking it for at least 3 months. Without a stated amount, you cannot tell how that sits with short-course guidance. Our FemiCore safety page covers who should avoid bearberry.

Not disclosed. The bearberry amount and its arbutin content.

Cranberry extract

What it is. A fruit extract whose A-type proanthocyanidins (PACs) reduce how well E. coli bacteria stick to the urinary tract.

What research shows. The 2023 Cochrane review found cranberry products can reduce repeat UTIs in women who are prone to them. Earlier reviews were mixed, and the effect depends on the PAC dose. It was studied for infections, not for leaks or urgency.

Not disclosed. The extract amount and the PAC content, which is the number that matters most for cranberry.

Granular berberine

What it is. A plant compound.

What research shows. Berberine has good human data for blood sugar and cholesterol, from studies using roughly 1,000 to 1,500 mg a day. Evidence for the bladder is lacking.

Why it matters for safety. Berberine accounts for most of the possible drug interactions in this formula, including with diabetes medicine and drugs broken down by the CYP3A4 and CYP2D6 liver enzymes.

Not disclosed. The berberine dose.

The five probiotic species

Lactobacillus crispatus

What it is. A Lactobacillus species, and the one with the most relevant research behind it.

What research shows. Since about 2012, sequencing studies from Loyola University Chicago and others have found that the female bladder is not sterile. Some of those studies saw fewer Lactobacillus in women with urgency incontinence. Separately, a small placebo-controlled trial found an L. crispatus product reduced repeat UTIs. That product was used vaginally, not swallowed, and it measured infections, not bladder control.

Not disclosed. The CFU count and the strain code.

L. acidophilus, L. plantarum, L. gasseri and L. casei

What they are. Four more Lactobacillus species, named by species only.

What research shows. In the research we reviewed for this page, none of these four was tested for bladder symptoms. The wider urinary microbiome idea is plausible but early. It does not show that swallowing probiotics changes bladder symptoms.

Why strain codes matter. Probiotic effects are strain-specific. A species name tells you the family, not the exact organism that was studied.

Not disclosed. CFU counts and strain codes for all four.

What the label leaves out

These are the items we looked for and could not find on the label or the official site:

• Individual doses for all nine ingredients
• The probiotic CFU count
• Probiotic strain codes
• Cranberry PAC content
• Bearberry arbutin content
• Berberine dose
• A certificate of analysis

Missing item	Why it matters to you
CFU count	You cannot tell how many live bacteria a capsule holds or compare it with another probiotic
Strain codes	Effects are strain-specific, so research on a species may not apply
Cranberry PAC content	The cranberry effect depends on PAC dose
Bearberry arbutin content	Bearberry guidance is for short courses, and the amount decides how much that matters
Berberine dose	Human studies used about 1,000 to 1,500 mg a day, and the dose also shapes interaction risk
Certificate of analysis	There is no published test result showing what is actually in the capsule

If those gaps matter to you, there is a simple way to act on them:

1. Write down the three numbers that matter most to you, for example CFU count, PAC content and berberine dose.
2. Ask the seller’s support team for them before you order.
3. If you take regular medicine, show the nine names to your pharmacist, with berberine at the top.
4. Decide with the answers in hand, or without them if none come back.

Seals shown next to the ingredients

The official site shows five seals: GMP Certified, Made in USA with imported ingredients, Natural ingredients, Made in an FDA registered facility, and Non-GMO. The site does not name the manufacturer or the certifier. “Made in an FDA registered facility” refers to the factory’s registration with the FDA. The FDA does not pre-approve supplements of any brand, so the seal is about where FemiCore is made. Our FemiCore official website guide explains how to read each seal.

What this means for the formula as a whole

The two ingredients with the most relevant human data, cranberry and L. crispatus, were studied for repeat infections. The ingredient with good human data, berberine, was studied for something else. The rest have little or no human research for the bladder. That is the honest shape of the evidence. To see how each seller claim lines up with it, read the FemiCore benefits page. For how we weigh ingredient evidence, see our methodology, and for our verdict, see the FemiCore review.